Same experience here with GLP-1 therapy in patients. MounjBrad described it perfectly.

TrialNerd_Beth said:

I started my GLP-1 journey in October 2024 at 256 lbs with prediabetes and hypertension

Gonna push back on this one. GLP-1 therapy in patients over 65 is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

Want to share my personal experience related to GLP-1 therapy in patients over since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 262 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 72 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The GLP-1 therapy in aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Saving this for reference. Quality thread.

LeilaHI — that is really helpful context on GLP-1 therapy in patients. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.