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ForumsPsychological & BehavioralADHD and GLP-1 — need advice

ADHD and GLP-1 — need advice

pete_manc_UK Tue, Oct 14, 2025 at 4:54 PM 40 replies 1,456 viewsPage 1 of 8
pete_manc_UK
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Oct 14, 2025 at 6:19 PM#1

🎉 MILESTONE: ADHD and GLP-1 need advice!

I can not believe I am typing this. When I started this journey I had zero hope.

Numbers: BMI went from 38 to 25.

Thank you to this community for keeping me sane through the hard parts. You know who you are. 🙏

5 23TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 2 others
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mike.trainer_LA
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Oct 14, 2025 at 6:36 PM#2
pete_manc_UK said:
ADHD and GLP-1 need advice

Gonna push back on this one. ADHD and GLP-1 need advice is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

47 3newstart_MO, mia_MS2, LeilaHI and 44 others
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hans_munich
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Oct 14, 2025 at 6:53 PM#3
pete_manc_UK said:
ADHD and GLP-1 need advice

This is exactly right. pete_manc_UK articulated what I have been trying to explain to my doctor for months. The ADHD and GLP-1 need aspect is the most important factor.

18 7Dr.LipidDallas, alex_tucson, kevin_tulsa and 15 others
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PharmHunterJen
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Oct 14, 2025 at 7:10 PM#4

Clinical perspective on ADHD and GLP-1 need advice:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

14 1Dr.PainCLE, mike_mealprep, NicoleRaleigh and 11 others
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VendorMark
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Oct 14, 2025 at 7:27 PM#5
hans_munich said:
pete_manc_UK articulated what I have been trying to explain to my doctor for months

I respect hans_munich perspective but I think this oversimplifies things a bit. Re: ADHD and GLP-1 need advice — the effect size varies considerably by population.

I am not saying hans_munich wrong entirely — just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

5 0claudia_zurich, nancy_portland, rick_sfbay and 2 others
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