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ForumsPublic SquarePCOS and GLP-1 agonists — reproductive outcomes data Page 4

PCOS and GLP-1 agonists — reproductive outcomes data

MeganSA_TX Wed, Dec 31, 2025 at 6:28 AM 17 replies 787 viewsPage 4 of 4
BiostatsBrad
Member
456
2,345
Jul 2024
Durham, NC
Dec 31, 2025 at 12:08 PM#16

Congrats PharmacoVig_BOS!! Keep going — you're doing incredible. 🎉 👏

8 19LindaRN_retired, tommy_boulder, hyun_seoul and 5 others
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LarryQC_SD
Senior Member
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9,876
Jan 2024
San Diego, CA
Dec 31, 2025 at 12:25 PM#17

Saving this for reference. Top-tier content.

Last edited: Dec 31, 2025 at 1:25 PM
37 6paul_denver, TinaHashiRN, robert_kc and 34 others
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NicoleRaleigh
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1,567
Aug 2024
Raleigh, NC
Dec 31, 2025 at 12:42 PM#18

Want to share my personal experience related to PCOS and GLP-1 agonists since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 274 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 6 months later: I am down 74 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The PCOS and GLP-1 aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

36 23COA_Karl, MikeFit_NJ, InsuranceTom and 33 others
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FDA_TrackerJim
Senior Member
1,567
7,890
Feb 2024
Rockville, MD
Dec 31, 2025 at 12:59 PM#19

Relevant to PCOS and GLP-1 agonists — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 235 → 105 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Dec 31, 2025 at 3:59 PM
47 1Dr.LeslieOBGYN, MikeNYC_runner and 44 others
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patPC_UT
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890
Nov 2024
Park City, UT
Dec 31, 2025 at 1:16 PM#20

Want to share my personal experience related to PCOS and GLP-1 agonists since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 246 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 12 months later: I am down 81 lbs, my labs have normalized, and I am off 2 of my 3 medications. The PCOS and GLP-1 aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Dec 31, 2025 at 6:16 PM
28 7julia.endo, JessicaM_2024, TomFromTexas and 25 others
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