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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralCompulsive shopping reduction on GLP-1 — 6 month update Page 5

Compulsive shopping reduction on GLP-1 — 6 month update

KarenAZ_mom Wed, Oct 8, 2025 at 12:52 PM 22 replies 1,119 viewsPage 5 of 5
MounjBrad
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Oct 8, 2025 at 7:57 PM#21

mike_mod — that is really helpful context on Compulsive shopping. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

Last edited: Oct 9, 2025 at 12:57 AM
21 22patPC_UT, Dr.DermMIA, fiona_VT and 18 others
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traveltech_sara
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Oct 8, 2025 at 8:14 PM#22

To answer NicoleRaleigh's question specifically:

From a clinical standpoint, Compulsive shopping reduction is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

36 23LarryQC_SD, wanda_boise, NurseAsh_DET and 33 others
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sarah.morrison
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Oct 8, 2025 at 8:31 PM#23

Thank you MounjBrad! This is incredibly helpful. Bookmarking for later. 🙏

5 19tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 2 others
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dave_SLC
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Oct 8, 2025 at 8:48 PM#24

Relevant to Compulsive shopping reduction — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 209 → 109 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

22 5FranDenver, Dr.BariatricHTX, LindaRN_retired and 19 others
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PeptideSynthNJ
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Princeton, NJ
Oct 8, 2025 at 9:05 PM#25

Slightly tangential to Compulsive shopping but MounjBrad reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

39 0Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 36 others
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