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ForumsPublic SquareNovo Nordisk vs Eli Lilly — the GLP-1 market landscape in 2026

Novo Nordisk vs Eli Lilly — the GLP-1 market landscape in 2026

anders_CPH Mon, Dec 22, 2025 at 1:00 PM 22 replies 1,194 viewsPage 1 of 5
anders_CPH
Senior Member
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Feb 2024
Copenhagen, DK
Dec 22, 2025 at 2:25 PM#1

Can I just vent for a second about novo nordisk vs eli lilly the?

I know this forum is evidence-based and I love that about it, but sometimes you just need to let it out. I hit another plateau and I am frustrated.

Not looking for a fix necessarily — just solidarity. Anyone else going through this right now?

45 22CryptoCarl, MariaRD, AussieAnna and 42 others
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Dr.ObesityMed
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Nov 2023
Denver, CO
Online
Dec 22, 2025 at 2:42 PM#2

anders_CPH's experience with Novo Nordisk vs Eli Lilly resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I am on a different medication. But the overall trajectory has been remarkably similar. Down 59 lbs in 14 months.

One thing I would add that anders_CPH did not mention: my sleep quality improved dramatically.

13 14PharmacoVig_BOS, SurmountFan_IN, PeptideChemSF and 10 others
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paige_pharma
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Sep 2024
Omaha, NE
Dec 22, 2025 at 2:59 PM#3

Thanks for sharing this, anders_CPH. A few questions about your Novo Nordisk vs Eli experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Novo Nordisk vs?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

21 20adam_van, Dr.SurgeonPGH, rachel_ABQ and 18 others
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anders_CPH
Senior Member
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7,234
Feb 2024
Copenhagen, DK
Dec 22, 2025 at 3:16 PM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Novo Nordisk vs Eli Lilly.

To answer paige_pharma: I started tracking everything in a spreadsheet from day 1.

Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

37 11BethLabQueen, ChrisMacros, KetoKyle and 34 others
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Dr.PathRoch
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Jun 2024
Rochester, MN
Dec 22, 2025 at 3:33 PM#5

Adding my data to this Novo Nordisk vs Eli Lilly discussion:

MetricBaselineMonth 5Month 8
Weight242 lbs227 lbs197 lbs
A1C6.6%6.0%5.4%
hsCRP6.04.00.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

Last edited: Dec 22, 2025 at 9:33 PM
30 3Dr.MetabolicMD, RetaRick_CA, JenPlateau and 27 others
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