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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralSleep quality changes on GLP-1 — my results so far Page 5

Sleep quality changes on GLP-1 — my results so far

ricardo_MIA Fri, Sep 19, 2025 at 6:52 AM 41 replies 1,867 viewsPage 5 of 9
julia.endo
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Sep 19, 2025 at 1:57 PM#21

Congrats ricardo_MIA!! You should be so proud of yourself. 🎉

20 16anna.melb_AU, mark_tokyo, hans_munich and 17 others
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VanRx_Mike
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Vancouver, CA
Sep 19, 2025 at 2:14 PM#22

Reading this thread on Sleep quality changes on hits close to home. Dad of 2 checking in — I started at 273 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 48 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Sleep quality — take the leap. It was the best health decision I have ever made. ❤️

12 5MikeNYC_runner and 9 others
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Dr.CardioMD
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Sep 19, 2025 at 2:31 PM#23

As a healthcare provider, I want to add some clinical context to this discussion on Sleep quality changes on GLP-1 my.

Building on what julia.endo said — the evidence base here is well-established. The key publications to reference are from the FLOW program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
26 18tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 23 others
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Dr.EM_Chicago
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Sep 19, 2025 at 2:48 PM#24

VanRx_Mike — wow. This community is amazing.

39 12lucas_SP_BR, lisa_labSD, adam_van and 36 others
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NicoleRaleigh
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Aug 2024
Raleigh, NC
Sep 19, 2025 at 3:05 PM#25

Adding my data to this Sleep quality changes on discussion:

MetricBaselineMonth 5Month 8
Weight266 lbs241 lbs221 lbs
A1C7.0%6.0%5.4%
hsCRP5.04.00.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

43 1mike_nyc, VendorMark, COA_Karl and 40 others
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