Nov 23, 2025 at 1:13 PM#11
100%. My provider said the same thing about Loose skin after.
33 17julia.endo, JessicaM_2024, TomFromTexas and 30 others
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Nov 23, 2025 at 1:30 PM#12
Reading this thread on Loose skin after major hits close to home. Dad of 2 checking in — I started at 285 lbs and felt like I would tried everything.
11 months on tirz and I am a different person. Not just the 60 lbs lost — my energy, my mood, my relationship with food. All transformed.
If you are on the fence about Loose skin after — take the leap. It was the best health decision I have ever made. ❤️
49 14PharmD_Rodriguez, julia.endo, JessicaM_2024 and 46 others
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Nov 23, 2025 at 1:47 PM#13
Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.
Thread quality is excellent — keep it up. 👍
47 8RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 44 others
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View ResultsNov 23, 2025 at 2:04 PM#14
Relevant to Loose skin after major weight — here is my latest bloodwork comparison:
Key improvements: A1C 8.4% → 5.5%, triglycerides 197 → 97 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
46 17TirzTom, TrialTracker_MD, JennaRN and 43 others
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Nov 23, 2025 at 2:21 PM#15
Congrats Dr.KarenChen!! You should be so proud of yourself. 🎉
18 19Dr.DermMIA, fiona_VT, denise_HTX and 15 others
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