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ForumsCompounding & Formulation503A vs 503B compounding — what worked for you? Page 2

503A vs 503B compounding — what worked for you?

tammy_FL Fri, Jan 16, 2026 at 1:31 AM 10 replies 770 viewsPage 2 of 2
mike_nyc
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Jan 16, 2026 at 4:21 AM#6

This is incredibly helpful, thank you all. My doctor recommended a 503B facility called Empower. I looked them up and they're on the FDA registered list. Feeling much better about this now.

One more question — should I ask for the COA before or after filling the prescription? Is that a normal thing patients do? I don't want to come across as difficult. 😅

13 22maya_sedona, stefan_berlin, Dr.EM_Chicago and 10 others
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CanadaChris
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Jan 16, 2026 at 4:38 AM#7

Ask after you receive it — the COA is batch-specific so you need your lot number first. And don't worry about being "difficult." Any pharmacy worth using will happily provide a COA. If they refuse or act weird about it, that's a red flag the size of Texas. 🚩

Last edited: Jan 16, 2026 at 10:38 AM
41 11stefan_berlin, Dr.EM_Chicago, pete_RVA and 38 others
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TrialNerd_Beth
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Jan 16, 2026 at 4:55 AM#8

Pinning this thread as it's one of the best 503A vs 503B breakdowns we've had. Thanks to our pharmacy and compounding experts for the detailed input.

Quick mod note: please don't post direct links to purchase from specific pharmacies. Discussion and naming is fine, but we can't have the forum become a storefront. Thanks all. 👍

37 0TomTeleRx, DoseLogDan, SleepFixSam and 34 others
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