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ForumsInternationalWhy is it SO much cheaper in Mexico and is it safe — my results so far

Why is it SO much cheaper in Mexico and is it safe — my results so far

TrialNerd_Beth Sat, Aug 30, 2025 at 12:00 PM 13 replies 1,115 viewsPage 1 of 3
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TrialNerd_Beth
Senior Member
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Jan 2024
Bethesda, MD
Aug 30, 2025 at 1:25 PM#1

Why is it SO much cheaper in Mexico and is it safe — my results so far

Curious where everyone stands on this. I have seen strong opinions both ways in other threads and want to get a proper read on the community consensus.

For context: why is it so much cheaper is something I've been going back and forth on. Some members seem to swear by one approach, others recommend the opposite.

Drop your experience below — even if it is just a quick "this worked" or "this did not work" that helps. Detailed responses obviously welcome too.

Let's get some data points going 📊

7 21RickReta_CO, PharmHunterJen, TomTeleRx and 4 others
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Dr.RenalNash
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Mar 2024
Nashville, TN
Aug 30, 2025 at 1:42 PM#2

TrialNerd_Beth's experience with Why is it SO much cheaper resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 40 lbs in 5 months.

One thing I would add that TrialNerd_Beth did not mention: the relationship with food fundamentally changed.

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sarah_nash92
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Nashville, TN
Aug 30, 2025 at 1:59 PM#3

Thanks for sharing this, TrialNerd_Beth. A few questions about your Why is it SO much experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about Why is it SO?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

16 20ZaraB_AL, JakeSmashed95, NauseaFreeNow and 13 others
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TrialNerd_Beth
Senior Member
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Jan 2024
Bethesda, MD
Aug 30, 2025 at 2:16 PM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Why is it SO much cheaper.

To answer sarah_nash92: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Aug 30, 2025 at 6:16 PM
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labquiet_amy
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Cambridge, MA
Aug 30, 2025 at 2:33 PM#5

Relevant to Why is it SO much cheaper in — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 193 → 93 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

45 8pete_manc_UK, anna.melb_AU, mark_tokyo and 42 others
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