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Forumsβ€ΊPublic Squareβ€ΊWeek 3 update - feeling like garbage tbh

Week 3 update - feeling like garbage tbh

JessicaH_TX Wed, Nov 12, 2025 at 3:43 PM 9 replies 940 viewsPage 1 of 2
JessicaH_TX
Senior Member
4,123
13,456
Dec 2023
Houston, TX
Nov 12, 2025 at 5:08 PM#1

Okay I need help with this β€” week 3 update - feeling like.

I have been dealing with this for about a month and I am getting frustrated. Googling just gives me contradictory information and my provider does not seem to take it seriously.

Please tell me someone here has been through this and come out the other side. What did you do? What finally worked?

I know there are some really knowledgeable people on this forum so I am hoping someone can point me in the right direction. 😩

21 1wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 18 others
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Dr.BariatricHTX
Senior Member
1,456
7,234
Feb 2024
Houston, TX
Nov 12, 2025 at 5:25 PM#2

JessicaH_TX's experience with Week 3 update - feeling resonates deeply with mine. I went through almost the identical process β€” starting dose, titration timeline, side effects, everything.

The main difference: I started 3 months later. But the overall trajectory has been remarkably similar. Down 46 lbs in 11 months.

One thing I would add that JessicaH_TX did not mention: the mental health improvements were just as significant.

6 13pete_RVA, CarlaRPh_TPA, steph_laguna and 3 others
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rachel_ABQ
Member
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890
Dec 2024
Albuquerque, NM
Nov 12, 2025 at 5:42 PM#3

Thanks for sharing this, JessicaH_TX. A few questions about your Week 3 update - experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about Week 3 update -?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Nov 12, 2025 at 10:42 PM
41 10AmyNC_wife, SkepticalSean, Dr.CardioMD and 38 others
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JessicaH_TX
Senior Member
4,123
13,456
Dec 2023
Houston, TX
Nov 12, 2025 at 5:59 PM#4

OP here β€” wow, did not expect this much response! Thank you all for the thoughtful replies on Week 3 update - feeling.

To answer rachel_ABQ: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion β€” this is exactly why I posted in a science-based community. πŸ™

Last edited: Nov 12, 2025 at 9:59 PM
22 8Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 19 others
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Dr.AddMedPHL
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Mar 2024
Philadelphia, PA
Nov 12, 2025 at 6:16 PM#5

Relevant to Week 3 update - feeling like β€” here is my latest bloodwork comparison:

Key improvements: A1C 8.0% β†’ 5.3%, triglycerides 219 β†’ 119 mg/dL, hsCRP 6.0 β†’ 1.3 mg/L. All on tirzepatide for 11 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Nov 12, 2025 at 8:16 PM
47 15JessicaM_2024, TomFromTexas, mike.trainer_LA and 44 others
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