Dr.NutriCornell said:

Wait so orforglipron means no is not that straightforward in my experience

This is exactly right. Dr.NutriCornell articulated what I have been trying to explain to my doctor for months. The Wait so orforglipron aspect is the most important factor.

Reading this thread on Wait so orforglipron hits close to home. Night shift nurse — I started at 279 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 54 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Wait so orforglipron — take the leap. It was the best health decision I have ever made. ❤️

Dr.GutHealth — that is really helpful context on Wait so orforglipron. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

To answer SallyK_inj's question specifically:

From a clinical standpoint, Wait so orforglipron means no is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

Bookmarked 📌 The Wait so orforglipron info in this thread is essential. Coming back to this for sure.