Just had to share this with someone who would understand — glp-1 and addiction pathways anyone have.

Got my latest A1C and I am genuinely emotional right now. 12 months in and the progress is real.

Details in the comments but wanted to start this thread because I think others going through the same thing need to see that it works.

sean_dublin's experience with GLP-1 and addiction resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 56 lbs in 11 months.

One thing I would add that sean_dublin did not mention: the relationship with food fundamentally changed.

Thanks for sharing this, sean_dublin. A few questions about your GLP-1 and addiction experience:

1. What dose are you currently on?
2. How long before you noticed significant changes?
3. Did your doctor have any specific recommendations about GLP-1 and addic?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on GLP-1 and addiction.

To answer LibrarianMeg: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Relevant to GLP-1 and addiction pathways — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 249 → 119 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.