Slightly tangential to Does anyone else feel but steve_okc reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Relevant to Does anyone else feel like — here is my latest bloodwork comparison:
Key improvements: A1C 7.6% → 5.5%, triglycerides 229 → 99 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.
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View ResultsWant to share my personal experience related to Does anyone else feel like since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 255 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 12 months later: I am down 70 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Does anyone else aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
BiostatsBrad — that is really helpful context on Does anyone else feel. Follow-up question: did you change anything about your diet at the same time?
I am in a similar situation (month 2) and trying to set realistic expectations.