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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPsychological & BehavioralQuality of life improvements on GLP-1 — looking for input Page 3

Quality of life improvements on GLP-1 — looking for input

marco_milano Wed, Jul 2, 2025 at 2:55 AM 17 replies 1,253 viewsPage 3 of 4
zoe_NC
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1,234
Nov 2024
Charlotte, NC
Jul 2, 2025 at 7:10 AM#11

amy_econ_NJ — wow. This community is amazing.

26 23Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 23 others
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tammy_FL
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890
Nov 2024
Tampa, FL
Jul 2, 2025 at 7:27 AM#12

Slightly tangential to Quality of life but marco_milano reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

20 23alex_tucson, kevin_tulsa, Dr.PainCLE and 17 others
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A1cHero_PHX
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523
2,678
Jul 2024
Phoenix, AZ
Jul 2, 2025 at 7:44 AM#13

Thanks for sharing this, marco_milano. A few questions about your Quality of life experience:

  1. What dose worked best for you?
  2. How long before you noticed appetite suppression kicking in?
  3. Did your endo have any specific recommendations about Quality of life?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Jul 2, 2025 at 12:44 PM
8 21tampaLisa73, KarenAZ_mom, zoe_NC and 5 others
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marco_milano
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345
1,456
Jul 2024
Milan, IT
Jul 2, 2025 at 8:01 AM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Quality of life.

To answer tammy_FL: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Jul 2, 2025 at 12:01 PM
6 24tammy_FL, Dr.LipidDallas, alex_tucson and 3 others
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NicoleRaleigh
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Aug 2024
Raleigh, NC
Jul 2, 2025 at 8:18 AM#15

Relevant to Quality of life improvements — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 209 → 109 mg/dL, hsCRP 8.0 → 0.9 mg/L. All on tirzepatide for 13 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

22 0mike_nyc, VendorMark, COA_Karl and 19 others
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