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ForumsOral GLP-1 AgonistsOral semaglutide 50mg (Rybelsus HD) — 12 month update Page 9

Oral semaglutide 50mg (Rybelsus HD) — 12 month update

LibrarianMeg Mon, Mar 4, 2024 at 6:09 AM 44 replies 2,300 viewsPage 9 of 9
josh_phd_bmore
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Baltimore, MD
Mar 4, 2024 at 6:54 PM#41

Relevant to Oral semaglutide 50mg — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 223 → 93 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

26 10NurseKim_ATL, paul_denver, TinaHashiRN and 23 others
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bbq_ray_KC
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378
1,678
Jul 2024
Kansas City, KS
Mar 4, 2024 at 7:11 PM#42

Want to share my personal experience related to Oral semaglutide 50mg since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 279 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 8 months later: I am down 74 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Oral semaglutide aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

Last edited: Mar 4, 2024 at 9:11 PM
10 21MikeFit_NJ, InsuranceTom, WendyG_ATL and 7 others
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sarah_nash92
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Jun 2024
Nashville, TN
Mar 4, 2024 at 7:28 PM#43

sarah_TO — that is really helpful context on Oral semaglutide 50mg. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

24 24ZaraB_AL, JakeSmashed95, NauseaFreeNow and 21 others
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InsuranceTom
Senior Member
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Mar 2024
Connecticut
Mar 4, 2024 at 7:45 PM#44

Want to share my personal experience related to Oral semaglutide 50mg since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 251 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 14 months later: I am down 81 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Oral semaglutide aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

10 1matt_MKE, Dr.ReproEndo, lucas_SP_BR and 7 others
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hyun_seoul
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Jul 2024
Seoul, KR
Mar 4, 2024 at 8:02 PM#45

sarah_nash92 — that is really helpful context on Oral semaglutide 50mg. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.

Last edited: Mar 5, 2024 at 12:02 AM
22 17LipidDoc_ATL, BariatricNurseD, MASHdoc_SA and 19 others
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