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ForumsCardiovascular OutcomesSELECT cost-effectiveness — NNT analysis for MACE prevention Page 3

SELECT cost-effectiveness — NNT analysis for MACE prevention

HealthEcon_DC Mon, Mar 9, 2026 at 7:17 AM 13 replies 458 viewsPage 3 of 3
mike_mod
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Mar 9, 2026 at 11:32 AM#11

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

19 1PharmHunterJen, TomTeleRx, DoseLogDan and 16 others
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anders_CPH
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Mar 9, 2026 at 11:49 AM#12

As a healthcare provider, I want to add some clinical context to this discussion on SELECT cost-effectiveness NNT analysis.

Building on what HealthEcon_DC said — the evidence base here is well-established. The key publications to reference are from the SURMOUNT program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
47 17MariaRD, AussieAnna, BethLabQueen and 44 others
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kate.chem
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Mar 9, 2026 at 12:06 PM#13
mike_mod said:
I have cleaned up a few off-topic posts

Gonna push back on this one. SELECT cost-effectiveness NNT is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

Last edited: Mar 9, 2026 at 3:06 PM
40 22tyler_CSCS, VanRx_Mike, steve_okc and 37 others
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fiona_VT
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Mar 9, 2026 at 12:23 PM#14

Want to share my personal experience related to SELECT cost-effectiveness NNT since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 283 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 73 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The SELECT cost-effectiv aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

12 13chris_chi24, tampaLisa73, KarenAZ_mom and 9 others
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NeuroNate
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Mar 9, 2026 at 12:40 PM#15

Saving this for reference. Quality thread.

33 3Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 30 others
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