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Evidence-based GLP-1 & peptide discussion since 2023
ForumsPublic SquareIs there a ceiling effect for GLP-1-mediated weight loss? — my results so far Page 2

Is there a ceiling effect for GLP-1-mediated weight loss? — my results so far

raj_cambridge Fri, Sep 19, 2025 at 6:20 AM 33 replies 1,411 viewsPage 2 of 7
wendy_avl
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Oct 2024
Asheville, NC
Sep 19, 2025 at 9:10 AM#6

your morning routine description is literally poetry 😂 But seriously, even just the water-first-coffee-second change will probably help. Let me know how it goes!

I actually did IF for the first 2 months and switched to eating breakfast for exactly the reasons Sam described. Anecdotally, my DEXA results got better after I started distributing protein more evenly. Could be coincidence but the science supports it.

Great points about consistent wake time. I'm religious about my 5:45 alarm even on weekends now. My wife thinks I'm insane but my sleep tracker shows clearly better sleep quality.

Last edited: Sep 19, 2025 at 3:10 PM
29 2SleepFixSam, PurityPaulOR, MaxMetOK and 26 others
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steve_okc
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Jul 2024
Oklahoma City, OK
Sep 19, 2025 at 9:27 AM#7

Genuinely curious — does anyone have a version of this for people who work evenings/nights? I'm a nurse and my schedule is chaotic. Some weeks I'm 7am-3pm, others I'm 3pm-11pm or even night shifts. The idea of a consistent morning routine is laughable.

What I CAN control:

  • First meal whenever I wake up: high protein (I prep egg muffins for grab and go)
  • Water with electrolytes within 30 min of waking
  • 10 min walk outside if daylight exists during my wake hours
  • Supplements at the same point in my "morning" regardless of clock time

It's not as clean as Max's routine but it's what I can manage with my job. Shift work + GLP-1 is a special kind of challenge.

35 19JakeSmashed95, NauseaFreeNow, SteveThurs and 32 others
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CryptoCarl
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May 2024
Arizona
Sep 19, 2025 at 9:44 AM#8

I think what you're doing is exactly right — it's not about the clock time, it's about the sequence relative to YOUR wake-up. Your "morning routine" at 2pm is just as valid as mine at 5:45am. The principles (hydrate → light exposure → protein → then caffeine) can be applied to any wake time.

Shift workers honestly impress me the most because you're doing all of this on hard mode. The fact that you're prepping egg muffins and thinking about this stuff while working nursing shifts is incredible. 💪

46 5AussieAnna, BethLabQueen, ChrisMacros and 43 others
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SleepFixSam
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212
678
Nov 2024
Hawaii
Sep 19, 2025 at 10:01 AM#9

UPDATE: tried the water-before-coffee thing this morning. it took every ounce of willpower not to go straight for the coffee machine but I did it. Drank 500ml water, waited 15 min, then had my coffee WITH a couple eggs.

Result: NO morning nausea for the first time in weeks????? Is this what not feeling terrible feels like??? I've been sabotaging myself this whole time with the empty-stomach coffee????

okay Max you win. I'm a convert. still not waking up at 5:45 though, lets not get crazy 😂

22 5denise_HTX, raj_cambridge, ingrid_STO and 19 others
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JennaRN
Senior Member
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Mar 2024
Colorado
Online
Sep 19, 2025 at 10:18 AM#10

YES!! The empty-stomach coffee thing is such a common GLP-1 mistake and nobody warns you about it. Glad it helped! And 5:45 is definitely optional — the routine works at any time. The important thing is the ORDER, not the hour. Welcome to the no-nausea club 🎉

Last edited: Sep 19, 2025 at 11:18 AM
17 16SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 14 others
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