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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesEchocardiographic changes on GLP-1 — LV mass and diastolic function Page 2

Echocardiographic changes on GLP-1 — LV mass and diastolic function

Dr.CardioMD Wed, Mar 4, 2026 at 6:58 AM 20 replies 460 viewsPage 2 of 4
matt_MKE
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Milwaukee, WI
Mar 4, 2026 at 9:48 AM#6

Subscribing to this thread. Echocardiographic changes is exactly what I've been researching. 🙏

Last edited: Mar 4, 2026 at 12:48 PM
50 17andrew_nyc, Dr.EndoEP, GraceAZ_72 and 47 others
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Dr.CardioMD
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Mar 4, 2026 at 10:05 AM#7

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Echocardiographic changes.

To answer Dr.ObesityMed: my doctor and I discussed the options and went with brand.

Quick update: I have noticed more improvement since posting this. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Mar 4, 2026 at 4:05 PM
21 6Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 18 others
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bri_stats
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May 2024
Seattle, WA
Mar 4, 2026 at 10:22 AM#8

Adding my data to this Echocardiographic changes discussion:

MetricBaselineMonth 4Month 6
Weight264 lbs219 lbs199 lbs
A1C6.8%6.2%5.2%
hsCRP8.03.00.6

Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

17 13TomFromTexas, mike.trainer_LA, sarah_nash92 and 14 others
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julia.endo
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Feb 2024
Cincinnati, OH
Mar 4, 2026 at 10:39 AM#9

+1 to Dr.CardioMD. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with Echocardiographic changes.

Last edited: Mar 4, 2026 at 4:39 PM
7 7jason_sac26, chris_chi24, tampaLisa73 and 4 others
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NurseLeah_Nash
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Sep 2024
Nashville, TN
Mar 4, 2026 at 10:56 AM#10

Slightly tangential to Echocardiographic changes but anna.melb_AU reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

50 17Dr.NateNeph, PharmD_Rodriguez, julia.endo and 47 others
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