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ForumsCompounding & FormulationInternational compounding regulations — 6 month update Page 3

International compounding regulations — 6 month update

Admin Thu, Nov 13, 2025 at 11:41 AM 12 replies 1,033 viewsPage 3 of 3
Dr.RheumBOS
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567
2,345
Apr 2024
Boston, MA
Nov 13, 2025 at 3:56 PM#11

lisa_labSD — wow. This community is amazing.

44 3pam_stl, wei_SG, cory_ATX and 41 others
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DoseLogDan
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567
Feb 2025
Montana
Nov 13, 2025 at 4:13 PM#12

Slightly tangential to International compounding but Admin reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

20 0Dr.AddMedPHL, newstart_MO, mia_MS2 and 17 others
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dan_philly
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456
2,123
Jul 2024
Philadelphia, PA
Nov 13, 2025 at 4:30 PM#13

Thanks for sharing this, Admin. A few questions about your International experience:

  1. What dose are you currently on?
  2. How long before you noticed significant changes?
  3. Did your doctor have any specific recommendations about International?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

27 17SkepticalSean, Dr.CardioMD, EndoResFellow and 24 others
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Admin
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Oct 2023
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Nov 13, 2025 at 4:47 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on International compounding.

To answer DoseLogDan: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

Last edited: Nov 13, 2025 at 8:47 PM
47 9BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 44 others
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VendorMark
Senior Member
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Jan 2024
Texas
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Nov 13, 2025 at 5:04 PM#15

Relevant to International compounding — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 225 → 95 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

11 16claudia_zurich, nancy_portland, rick_sfbay and 8 others
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