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ForumsPublic SquareNovo Nordisk CagriSema Phase 3 results — need advice Page 4

Novo Nordisk CagriSema Phase 3 results — need advice

mike_mod Sat, Aug 23, 2025 at 8:31 PM 43 replies 1,982 viewsPage 4 of 9
mike_mod
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Aug 24, 2025 at 2:11 AM#16

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Novo Nordisk CagriSema.

To answer anders_CPH: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

15 11PharmHunterJen, TomTeleRx, DoseLogDan and 12 others
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NicoleRaleigh
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Aug 24, 2025 at 2:28 AM#17

Relevant to Novo Nordisk CagriSema Phase 3 — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 205 → 105 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

36 16MikeFit_NJ, InsuranceTom, WendyG_ATL and 33 others
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Dr.LipidDallas
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Aug 24, 2025 at 2:45 AM#18

100%. My provider said the same thing about Novo Nordisk.

Last edited: Aug 24, 2025 at 4:45 AM
30 6cory_ATX, lori_vegas, Dr.PulmRoch and 27 others
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HPLC_Greg
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Aug 24, 2025 at 3:02 AM#19

Slightly tangential to Novo Nordisk CagriSema but emma_london reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

36 9Dr.MetabolicMD, RetaRick_CA, JenPlateau and 33 others
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nick_SD_fit
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Aug 24, 2025 at 3:19 AM#20
mike_mod said:
Thank you all for the thoughtful replies on Novo Nordisk CagriSema

This is exactly right. mike_mod articulated what I have been trying to explain to my doctor for months. The Novo Nordisk CagriSema aspect is the most important factor.

20 7SurmountFan_IN, PeptideChemSF, A1cHero_PHX and 17 others
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