🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsOral GLP-1 AgonistsOral semaglutide bioavailability optimization — 12 month update Page 2

Oral semaglutide bioavailability optimization — 12 month update

jim_asheville Sun, Nov 12, 2023 at 4:58 PM 58 replies 3,516 viewsPage 2 of 12
LabKate
Senior Member
2,678
11,234
Jan 2024
Oregon
Nov 12, 2023 at 7:48 PM#6

I'm going to rant for a second: it's absolutely INSANE that we have a medication that works this well for obesity and diabetes, and people can't get it because of a "shortage." This has been going on for over two years. At some point it stops being a shortage and starts being a manufacturing failure.

Novo Nordisk's revenue from semaglutide was over $20 BILLION last year. They can afford to build more factories. The fact that patients are going weeks without their medication because the company can't keep up with demand is inexcusable.

rant over sorry 😤

35 14JenMemphis, pat_auckland, Dr.GastroMayo and 32 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
Nov 12, 2023 at 8:05 PM#7

Totally valid frustration. We have a shortage mega-thread pinned at the top of the forum that gets updated weekly with stock reports by region. I'd recommend checking there for real-time availability info.

Also reminder: please don't share specific pharmacy locations with stock publicly — it leads to pharmacy-hopping and worsens the shortage for local patients. DMs are fine.

20 9TomTeleRx, DoseLogDan, SleepFixSam and 17 others
Reply Quote Save Share Report
Dr.CardioMD
VIP Member
2,678
14,567
Dec 2023
Cleveland, OH
Nov 12, 2023 at 8:22 PM#8

UPDATE: Called a specialty pharmacy my doctor recommended and they were able to get my 1.7mg pen within 3 days. The regular chain pharmacies still show out of stock. Specialty pharmacies seem to have different supply channels.

Total time off: 17 days. Appetite definitely came back but not to pre-sema levels. Took my injection yesterday and already feeling the appetite suppression returning. Hopefully the shortage improves but I'm keeping this specialty pharmacy on speed dial going forward.

Thanks for all the advice everyone. This community keeps me sane 🙏

44 24tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 41 others
Reply Quote Save Share Report

PeptideMeter — Independent Peptide Analytics

Community-driven peptide testing and vendor rating platform. Transparent results. Unbiased analysis. Trusted by thousands.

View Results
oliver_london
Member
312
1,345
Aug 2024
London, UK
Nov 12, 2023 at 8:39 PM#9

glad you found it! I switched to compounded 3 months ago specifically because of the shortage situation and honestly I wish I'd done it sooner. Same results, never a supply issue, fraction of the cost. Just my experience.

30 12jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 27 others
Reply Quote Save Share Report

Similar Threads

Orforglipron Phase 3 ATTAIN-1 topline — oral non-peptide GLP-116 replies
Oral semaglutide 50mg (Rybelsus HD) — OASIS program results12 replies
Danuglipron BID dosing — Pfizer oral GLP-1 update7 replies
Oral vs injectable GLP-1: bioavailability and efficacy comparison5 replies
Orforglipron food interaction profile — no fasting requirement15 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register