🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesNNT for MACE prevention — semaglutide vs statin vs SGLT2i comparison Page 5

NNT for MACE prevention — semaglutide vs statin vs SGLT2i comparison

BiostatsBrad Sat, Feb 21, 2026 at 12:55 AM 26 replies 690 viewsPage 5 of 6
Dr.DermMIA
Member
456
2,123
May 2024
Miami, FL
Feb 21, 2026 at 8:00 AM#21

Subscribing to this thread. NNT for MACE prevention is exactly what I've been researching. 🙏

15 5LipidDoc_ATL, BariatricNurseD, MASHdoc_SA and 12 others
Reply Quote Save Share Report
SarahChen_PharmD
VIP Member
4,567
22,341
Dec 2023
San Diego, CA
Feb 21, 2026 at 8:17 AM#22

Slightly tangential to NNT for MACE prevention but LarryQC_SD reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Feb 21, 2026 at 11:17 AM
6 15NurseKim_ATL, paul_denver, TinaHashiRN and 3 others
Reply Quote Save Share Report
JakeSmashed95
Member
412
1,890
Aug 2024
Arkansas
Online
Feb 21, 2026 at 8:34 AM#23

Saving this for reference. Top-tier content.

50 12alex_tucson, kevin_tulsa, Dr.PainCLE and 47 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
BiostatsBrad
Member
456
2,345
Jul 2024
Durham, NC
Feb 21, 2026 at 8:51 AM#24

Slightly tangential to NNT for MACE prevention but LarryQC_SD reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

22 0james_edin, FranDenver, Dr.BariatricHTX and 19 others
Reply Quote Save Share Report
dave_SLC
Member
345
1,567
Aug 2024
Salt Lake City, UT
Feb 21, 2026 at 9:08 AM#25

Relevant to NNT for MACE prevention — here is my latest bloodwork comparison:

Key improvements: A1C 8.0% → 5.3%, triglycerides 235 → 105 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

46 16Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 43 others
Reply Quote Save Share Report

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register