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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesShould I be worried about my heart rate going up? Page 2

Should I be worried about my heart rate going up?

nick_newbie Fri, Feb 13, 2026 at 5:35 PM 9 replies 584 viewsPage 2 of 2
Dr.GutHealth
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Feb 13, 2026 at 8:25 PM#6
Dr.SurgeonPGH said:
— in my experience this comes down to a few key factors

Gonna push back on this one. Should I be worried about my heart is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.

4 2VanRx_Mike, steve_okc, dave_SLC and 1 other
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Dr.PathRoch
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Rochester, MN
Feb 13, 2026 at 8:42 PM#7

Adding my data to this Should I be worried about discussion:

MetricBaselineMonth 5Month 8
Weight266 lbs216 lbs221 lbs
A1C7.0%6.0%5.4%
hsCRP5.04.00.8

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

20 10InsuranceTom, WendyG_ATL, SaraMom3 and 17 others
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CanadaChris
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Feb 13, 2026 at 8:59 PM#8

Dr.CardioMD — wow. I've been looking for this exact info for weeks.

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VanRx_Mike
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May 2024
Vancouver, CA
Feb 13, 2026 at 9:16 PM#9

Slightly tangential to Should I be worried about but AussieAnna reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

11 9Dr.Martinez, mike_mod, SarahChen_PharmD and 8 others
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mike_mod
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Feb 13, 2026 at 9:33 PM#10

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

17 0PurityPaulOR, MaxMetOK, MounjBrad and 14 others
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