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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesDo the heart benefits go away if I stop taking it? Page 2

Do the heart benefits go away if I stop taking it?

SaraMom3 Sun, Feb 8, 2026 at 5:46 AM 7 replies 523 viewsPage 2 of 2
kate.chem
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Feb 8, 2026 at 8:36 AM#6
sarah.morrison said:
Short answer: it depends on your starting point

Gonna push back on this one. Do the heart benefits go away if I is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

39 20steve_okc, dave_SLC, FDA_TrackerJim and 36 others
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josh_phd_bmore
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Feb 8, 2026 at 8:53 AM#7

Adding my data to this Do the heart benefits go discussion:

MetricBaselineMonth 3Month 6
Weight276 lbs246 lbs201 lbs
A1C7.0%5.8%5.2%
hsCRP5.02.01.0

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

36 18Dr.ObesityLA, NurseKim_ATL, paul_denver and 33 others
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emma_london
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Feb 8, 2026 at 9:10 AM#8

Dr.SleepRoch — wow. This community is amazing.

45 17TomFromTexas, mike.trainer_LA, sarah_nash92 and 42 others
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JakeSmashed95
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Feb 8, 2026 at 9:27 AM#9

Slightly tangential to Do the heart benefits go but newstart_MO reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Feb 8, 2026 at 2:27 PM
24 7Dr.LipidDallas, alex_tucson, kevin_tulsa and 21 others
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mike_mod
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Feb 8, 2026 at 9:44 AM#10

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

48 5PurityPaulOR, MaxMetOK, MounjBrad and 45 others
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