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ForumsTirzepatide (Mounjaro / Zepbound)Compounded tirz stability at room temperature — 14-day data Page 2

Compounded tirz stability at room temperature — 14-day data

kate.chem Fri, Jan 23, 2026 at 9:09 AM 26 replies 804 viewsPage 2 of 6
LibrarianMeg
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Mar 2024
Baltimore, MD
Jan 23, 2026 at 11:59 AM#6

Wait I'm confused. My vial says 3mg not 5mg. Do I just use the same formula?

4 7Dr.NateNeph, PharmD_Rodriguez, julia.endo and 1 other
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MASHdoc_SA
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Aug 2024
San Antonio, TX
Jan 23, 2026 at 12:16 PM#7
Previously posted:
My vial says 3mg not 5mg. Do I just use the same formula?

Same exact formula, just different numbers. The universal formula is:

Volume to inject (mL) = Desired dose (mg) ÷ Concentration (mg/mL)

And concentration = Total mg in vial ÷ mL of BAC water added

So for your 3mg vial, if you add 1.5mL BAC water:

  • Concentration = 3mg / 1.5mL = 2mg/mL
  • 0.25mg dose = 0.25 / 2 = 0.125mL = 12.5 units (draw to halfway between 10 and 15)
  • 0.5mg dose = 0.5 / 2 = 0.25mL = 25 units

Or if you want easier numbers, add 1.2mL BAC water to get 2.5mg/mL, then 0.25mg = 10 units. Same as the 5mg vial example. The total number of doses per vial will be different of course (3mg total instead of 5mg).

14 12TrialTracker_MD, JennaRN, LabKate and 11 others
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BiostatsBrad
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Jul 2024
Durham, NC
Jan 23, 2026 at 12:33 PM#8

you are an absolute angel. I just did my first reconstitution and injection — 10 units, right in the belly, barely felt it. This community is the best. Thank you all so much!! 🙏🥹

Last edited: Jan 23, 2026 at 1:33 PM
16 7FranDenver, Dr.BariatricHTX, LindaRN_retired and 13 others
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Dr.RheumBOS
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Apr 2024
Boston, MA
Jan 23, 2026 at 12:50 PM#9

Pinning this thread. We get this question at least twice a week. Excellent explanations as always from our knowledgeable members. For anyone reading this in the future, we also have a reconstitution calculator in the Tools section of the wiki.

And a reminder: always verify your math before injecting. If something seems off, ask here or call your provider. It's never a dumb question when it comes to dosing.

Last edited: Jan 23, 2026 at 6:50 PM
40 8lori_vegas, Dr.PulmRoch, maya_sedona and 37 others
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