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Evidence-based GLP-1 & peptide discussion since 2023
Forumsβ€ΊCardiovascular Outcomesβ€ΊMy dad had a heart attack and now I am terrified - will GLP-1 help?

My dad had a heart attack and now I am terrified - will GLP-1 help?

FitDadDave Thu, Feb 5, 2026 at 7:22 AM 5 replies 485 viewsPage 1 of 1
FitDadDave
Member
534
2,678
Jul 2024
Minneapolis, MN
Feb 5, 2026 at 8:47 AM#1

Okay I need help with this β€” my dad had a heart attack.

I have been dealing with this for way too long and I am getting frustrated. Googling just gives me contradictory information and my endo does not seem to take it seriously.

Please tell me someone here has been through this and come out the other side. What did you do? What finally worked?

I know there are some really knowledgeable people on this forum so I am hoping someone can point me in the right direction. 😩

48 17Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 45 others
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Dr.MetabolicMD
VIP Member
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16,789
Jan 2024
Rochester, MN
Feb 5, 2026 at 9:04 AM#2

FitDadDave's experience with My dad had a heart attack resonates deeply with mine. I went through almost the identical process β€” starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 48 lbs in 13 months.

One thing I would add that FitDadDave did not mention: the relationship with food fundamentally changed.

Last edited: Feb 5, 2026 at 11:04 AM
1 1PedsEndoPhilly
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zoe_NC
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278
1,234
Nov 2024
Charlotte, NC
Feb 5, 2026 at 9:21 AM#3

Thanks for sharing this, FitDadDave. A few questions about your My dad had a heart experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about My dad had a?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Feb 5, 2026 at 10:21 AM
16 23james_edin, FranDenver, Dr.BariatricHTX and 13 others
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FitDadDave
Member
534
2,678
Jul 2024
Minneapolis, MN
Feb 5, 2026 at 9:38 AM#4

OP here β€” wow, did not expect this much response! Thank you all for the thoughtful replies on My dad had a heart attack.

To answer zoe_NC: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion β€” this is exactly why I posted in a science-based community. πŸ™

Last edited: Feb 5, 2026 at 12:38 PM
16 14wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 13 others
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SleepDoc_PDX
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Sep 2024
Portland, OR
Feb 5, 2026 at 9:55 AM#5

Relevant to My dad had a heart attack and β€” here is my latest bloodwork comparison:

Key improvements: A1C 8.4% β†’ 5.5%, triglycerides 241 β†’ 111 mg/dL, hsCRP 8.0 β†’ 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Feb 5, 2026 at 12:55 PM
12 5mel_PDX, Dr.AddMedPHL, newstart_MO and 9 others
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