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ForumsCardiovascular OutcomesHas anyone dealt with select trial: 20% mace reduction? Page 5

Has anyone dealt with select trial: 20% mace reduction?

Dr.SurgeonPGH Mon, Feb 2, 2026 at 6:00 AM 28 replies 808 viewsPage 5 of 6
nancy_portland
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Feb 2, 2026 at 1:05 PM#21

Want to share my personal experience related to Has anyone dealt with select since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 272 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 18 months later: I am down 52 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Has anyone dealt aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

44 18DebRD_ATL, KristenIndy, MarkLI_maint and 41 others
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mike_mod
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Feb 2, 2026 at 1:22 PM#22

Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.

No issues to report — carry on. 👍

Last edited: Feb 2, 2026 at 3:22 PM
5 4TomTeleRx, DoseLogDan, SleepFixSam and 2 others
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dan_philly
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Jul 2024
Philadelphia, PA
Feb 2, 2026 at 1:39 PM#23

Adding my data to this Has anyone dealt with discussion:

MetricBaselineMonth 5Month 8
Weight254 lbs219 lbs209 lbs
A1C6.8%6.0%5.4%
hsCRP8.04.01.2

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.6g/kg/day.

Last edited: Feb 2, 2026 at 4:39 PM
42 2SkepticalSean, Dr.CardioMD, EndoResFellow and 39 others
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SallyK_inj
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Jul 2024
Iowa
Feb 2, 2026 at 1:56 PM#24

PeptideChemSF — wow. I've been looking for this exact info for weeks.

15 7tane_welly, Dr.PathRoch, mona_PHX and 12 others
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BariatricNurseD
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Feb 2, 2026 at 2:13 PM#25
JakeBK_lifts said:
Has anyone dealt with is exactly what I've been researching

This is exactly right. JakeBK_lifts articulated what I have been trying to explain to my doctor for months. The Has anyone dealt with aspect is the most important factor.

32 21Dr.EndoIndy, tom_AK, josh_phd_bmore and 29 others
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