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Forumsβ€ΊTirzepatide (Mounjaro / Zepbound)β€Ί5mg doing nothing - should I ask to go up?

5mg doing nothing - should I ask to go up?

nick_newbie Fri, Jan 16, 2026 at 3:31 AM 10 replies 770 viewsPage 1 of 2
nick_newbie
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Jan 16, 2026 at 4:56 AM#1

Anyone else dealing with 5mg doing nothing - should i from a cost perspective?

I have been paying $280/month and I am trying to get insurance to cover it.

Share what you are paying and what you are getting β€” transparency helps everyone.

40 24robert_kc, dan_philly, MeganSA_TX and 37 others
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PurityPaulOR
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Jan 16, 2026 at 5:13 AM#2

To answer the question about 5mg doing nothing - should I ask to go up? β€” in my experience this comes down to a few key factors.

I have been dealing with this for over a year now, and what I have found is that individual responses really do vary. That said, the general consensus on 5mg doing nothing - should I seems solid.

What specifically worked for me: getting baseline labs before making any changes. I would suggest nick_newbie try the same approach and reporting back.

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paige_pharma
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Jan 16, 2026 at 5:30 AM#3
PurityPaulOR said:
β€” in my experience this comes down to a few key factors

Completely agree with PurityPaulOR. I would add that 5mg doing nothing - should I also has implications for long-term metabolic health that sometimes get overlooked in these discussions.

In my case, following a similar approach led to significant improvements compared to what I was doing before.

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KarenAZ_mom
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Jan 16, 2026 at 5:47 AM#4

Subscribing to this thread. 5mg doing nothing - is exactly what I've been researching. πŸ™

37 1LibrarianMeg, bri_stats, pete_manc_UK and 34 others
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NurseAsh_DET
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Jan 16, 2026 at 6:04 AM#5

As a pharmacist, I want to add some clinical context to this discussion on 5mg doing nothing - should I ask to go.

Building on what nick_newbie said β€” the evidence base here is robust. The key publications to reference are from the FLOW program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
1 14emily_PDX
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