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ForumsCardiovascular OutcomesSTEP-HFpEF: semaglutide in heart failure with preserved EF — need advice Page 3

STEP-HFpEF: semaglutide in heart failure with preserved EF — need advice

pam_stl Mon, Jan 26, 2026 at 6:17 PM 12 replies 546 viewsPage 3 of 3
KetoKyle
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Jul 2024
Utah
Jan 26, 2026 at 10:32 PM#11

Following this thread closely. STEP-HFpEF semaglutide in is something I'm actively working through.

13 23laura_annarbor, JenMemphis, pat_auckland and 10 others
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SleepDoc_PDX
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Sep 2024
Portland, OR
Jan 26, 2026 at 10:49 PM#12

Reading this thread on STEP-HFpEF semaglutide in hits close to home. Night shift nurse — I started at 263 lbs and felt like I would tried everything.

9 months on tirz and I am a different person. Not just the 38 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about STEP-HFpEF semagluti — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Jan 27, 2026 at 1:49 AM
24 9hank_denver, carlos_SATX, sophie_paris and 21 others
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Admin
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Jan 26, 2026 at 11:06 PM#13

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Jan 27, 2026 at 3:06 AM
43 21RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 40 others
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labquiet_amy
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Mar 2024
Cambridge, MA
Jan 26, 2026 at 11:23 PM#14

Relevant to STEP-HFpEF semaglutide in — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 235 → 105 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Last edited: Jan 27, 2026 at 1:23 AM
50 19bri_stats, pete_manc_UK, anna.melb_AU and 47 others
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lori_vegas
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Aug 2024
Las Vegas, NV
Jan 26, 2026 at 11:40 PM#15

Congrats KetoKyle!! Keep going — you're doing incredible. 🎉

Last edited: Jan 27, 2026 at 1:40 AM
8 10Dr.PathRoch, mona_PHX, andrew_nyc and 5 others
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