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ForumsCardiovascular OutcomesLp(a) on GLP-1 agonists — March 2026 Page 3

Lp(a) on GLP-1 agonists — March 2026

quinn_sf Mon, Jan 19, 2026 at 6:38 PM 19 replies 901 viewsPage 3 of 4
Admin
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Jan 19, 2026 at 10:53 PM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

Last edited: Jan 20, 2026 at 2:53 AM
10 14PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 7 others
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Dr.MetabolicMD
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Jan 19, 2026 at 11:10 PM#12

Clinical perspective on Lp(a) on GLP-1 agonists March 2026:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

26 12PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 23 others
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NurseKim_ATL
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Jan 19, 2026 at 11:27 PM#13
Admin said:
Consult your healthcare provider

I respect Admin perspective but I think this oversimplifies things a bit. Re: Lp(a) on GLP-1 agonists March — the subgroup analyses show meaningful heterogeneity.

I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

32 8ingrid_STO, pete_nash, hank_denver and 29 others
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anna.melb_AU
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Jan 19, 2026 at 11:44 PM#14

Reading this thread on Lp(a) on GLP-1 agonists hits close to home. Night shift nurse — I started at 287 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 62 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Lp(a) on GLP-1 — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Jan 20, 2026 at 3:44 AM
11 9tammy_FL, Dr.LipidDallas, alex_tucson and 8 others
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pat_auckland
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Jan 20, 2026 at 12:01 AM#15

Bookmarked 📌 The Lp(a) on GLP-1 info in this thread is essential. Coming back to this for sure.

43 24dan_philly, MeganSA_TX, LarryQC_SD and 40 others
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