🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsTirzepatide (Mounjaro / Zepbound)Anyone else get super cold on tirz? I am FREEZING Page 2

Anyone else get super cold on tirz? I am FREEZING

tammy_FL Wed, Dec 31, 2025 at 4:26 AM 11 replies 731 viewsPage 2 of 3
CanadaChris
Member
234
890
Nov 2024
Toronto, CA
Dec 31, 2025 at 7:16 AM#6

Congrats tammy_FL!! Keep going — you're doing incredible. 🎉 👏

22 0Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 19 others
Reply Quote Save Share Report
Dr.ObesityLA
VIP Member
3,567
19,876
Dec 2023
Los Angeles, CA
Dec 31, 2025 at 7:33 AM#7

Clinical perspective on Anyone else get super cold on tirz? I am:

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

Last edited: Dec 31, 2025 at 8:33 AM
7 3KarenAZ_mom, zoe_NC, Dr.ObesityLA and 4 others
Reply Quote Save Share Report
hannah_MT
New Member
23
89
Feb 2026
Bozeman, MT
Dec 31, 2025 at 7:50 AM#8

Subscribing to this thread. Anyone else get super is exactly what I've been researching. 🙏

Last edited: Dec 31, 2025 at 10:50 AM
9 24MaxMetOK, MounjBrad, nick_newbie and 6 others
Reply Quote Save Share Report

Sigma-Aldrich — Research-Grade Standards

Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.

Shop Reference Standards
steve_okc
Member
489
2,123
Jul 2024
Oklahoma City, OK
Dec 31, 2025 at 8:07 AM#9

Reading this thread on Anyone else get super hits close to home. Dad of 2 checking in — I started at 269 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 44 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Anyone else get — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Dec 31, 2025 at 12:07 PM
39 16CanadaChris, ZaraB_AL, JakeSmashed95 and 36 others
Reply Quote Save Share Report
Dr.SportsMedIN
Senior Member
1,456
6,789
Feb 2024
Indianapolis, IN
Dec 31, 2025 at 8:24 AM#10
CanadaChris said:
Keep going — you're doing incredible

This is exactly right. CanadaChris articulated what I have been trying to explain to my doctor for months. The Anyone else get super aspect is the most important factor.

Last edited: Dec 31, 2025 at 1:24 PM
7 22rachel_ABQ, traveltech_sara, AttorneyGrant and 4 others
Reply Quote Save Share Report

Similar Threads

SURMOUNT-5: Tirzepatide vs semaglutide head-to-head — full results11 replies
SURPASS 1-5 program: tirzepatide T2DM efficacy data compilation6 replies
Tirzepatide dual agonism: GIP + GLP-1 synergistic mechanism18 replies
5mg → 10mg → 15mg titration — clinical guidance and real-world data8 replies
Zepbound insurance coverage — payer-by-payer breakdown 20268 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register