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Evidence-based GLP-1 & peptide discussion since 2023
ForumsTirzepatide (Mounjaro / Zepbound)My appetite is literally gone is this normal at 10mg Page 2

My appetite is literally gone is this normal at 10mg

robert_kc Fri, Dec 26, 2025 at 9:12 PM 12 replies 727 viewsPage 2 of 3
JakeSmashed95
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Dec 27, 2025 at 12:02 AM#6

Congrats robert_kc!! You should be so proud of yourself. 🎉

Last edited: Dec 27, 2025 at 5:02 AM
12 24Dr.PainCLE, mike_mealprep, NicoleRaleigh and 9 others
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SarahChen_PharmD
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Dec 27, 2025 at 12:19 AM#7

Clinical perspective on My appetite is literally gone is this:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that the medication works best as part of a comprehensive approach.

For this specific question, I would recommend: getting comprehensive baseline labs first.

Last edited: Dec 27, 2025 at 3:19 AM
41 22NurseKim_ATL, paul_denver, TinaHashiRN and 38 others
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Dr.RheumBOS
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Dec 27, 2025 at 12:36 AM#8

Yep. My endo said the same thing about My appetite is.

Last edited: Dec 27, 2025 at 6:36 AM
12 19cory_ATX, lori_vegas, Dr.PulmRoch and 9 others
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MeganSA_TX
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Dec 27, 2025 at 12:53 AM#9

Reading this thread on My appetite is literally hits close to home. Night shift nurse — I started at 275 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 50 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about My appetite is — take the leap. It was the best health decision I have ever made. ❤️

14 10TomFromTexas, mike.trainer_LA, sarah_nash92 and 11 others
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Dr.PulmRoch
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Dec 27, 2025 at 1:10 AM#10
JakeSmashed95 said:
You should be so proud of yourself

This is exactly right. JakeSmashed95 articulated what I have been trying to explain to my friends for months. The My appetite is literally aspect is what made the difference for me.

14 21KristenIndy, MarkLI_maint, Dr.PeteFamMed and 11 others
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