Just wanted to say — for anyone reading this SURMOUNT-5 Tirzepati thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪
Slightly tangential to SURMOUNT-5 Tirzepatide vs but wei_SG reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Saving this for reference. Top-tier content.
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsWant to share my personal experience related to SURMOUNT-5 Tirzepatide vs since I think it might help others in a similar situation.
I started my GLP-1 journey in March 2025 at 248 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.
Now, 8 months later: I am down 48 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The SURMOUNT-5 Tirzepati aspect specifically was something that made a big difference in my journey.
This forum was my go-to resource throughout.
Relevant to SURMOUNT-5 Tirzepatide vs — here is my latest bloodwork comparison:
Key improvements: A1C 7.2% → 5.3%, triglycerides 239 → 109 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.
The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.