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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesHeart rate increase on GLP-1 — looking for input Page 6

Heart rate increase on GLP-1 — looking for input

LeilaHI Wed, Dec 31, 2025 at 3:14 AM 28 replies 1,322 viewsPage 6 of 6
pat_auckland
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Jun 2024
Auckland, NZ
Dec 31, 2025 at 11:44 AM#26

+1 to InsuranceTom. Especially the point about "This is incredibly helpful..." — I have seen the same in my own experience with Heart rate increase on.

Last edited: Dec 31, 2025 at 3:44 PM
3 20NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin
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Dr.PeteFamMed
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Jan 2024
Minneapolis, MN
Dec 31, 2025 at 12:01 PM#27

Bookmarked 📌 The Heart rate increase info in this thread is essential. Coming back to this for sure.

Last edited: Dec 31, 2025 at 1:01 PM
21 3tommy_boulder, hyun_seoul, jim_asheville and 18 others
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Dr.PulmRoch
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Jun 2024
Rochester, MN
Dec 31, 2025 at 12:18 PM#28

Clinical perspective on Heart rate increase on GLP-1 looking:

I have managed over 200 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

44 19AttorneyGrant, DebRD_ATL, KristenIndy and 41 others
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josh_phd_bmore
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Jul 2024
Baltimore, MD
Dec 31, 2025 at 12:35 PM#29

Want to share my personal experience related to Heart rate increase on GLP-1 since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 265 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 70 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Heart rate increase aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

Last edited: Dec 31, 2025 at 2:35 PM
23 11KarenAZ_mom, zoe_NC, Dr.ObesityLA and 20 others
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WendyG_ATL
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Apr 2024
Georgia
Dec 31, 2025 at 12:52 PM#30

Just wanted to say — for anyone reading this Heart rate increase thread who is feeling discouraged: it gets better. The first month are the hardest. Hang in there. 💪

Last edited: Dec 31, 2025 at 1:52 PM
49 21DebRD_ATL, KristenIndy, MarkLI_maint and 46 others
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