🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesSOUL trial preliminary data — need advice Page 2

SOUL trial preliminary data — need advice

roxy_nash Fri, Dec 26, 2025 at 8:00 PM 11 replies 847 viewsPage 2 of 3
chris_chi24
Member
389
1,678
Sep 2024
Chicago, IL
Dec 26, 2025 at 10:50 PM#6

Saving this for reference. Quality thread.

Last edited: Dec 27, 2025 at 1:50 AM
17 19nick_newbie, DadBodDave, AmyNC_wife and 14 others
Reply Quote Save Share Report
BenResearch_OR
Senior Member
2,456
11,234
Dec 2023
Oregon
Dec 26, 2025 at 11:07 PM#7

Slightly tangential to SOUL trial preliminary but SandraNC_45 reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Dec 27, 2025 at 12:07 AM
26 6PharmD_Rodriguez, julia.endo, JessicaM_2024 and 23 others
Reply Quote Save Share Report
sophie_paris
Member
212
890
Nov 2024
Paris, FR
Dec 26, 2025 at 11:24 PM#8

+1 to SandraNC_45. Especially the point about "A few questions about your SOUL trial pr..." — I have seen the same in my own experience with SOUL trial preliminary.

45 13MariaRD, AussieAnna, BethLabQueen and 42 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
bri_stats
Member
789
3,456
May 2024
Seattle, WA
Dec 26, 2025 at 11:41 PM#9

Dr.GutHealth — that is really helpful context on SOUL trial preliminary. Follow-up question: what labs did your doctor order to monitor this?

I am in a similar situation (just started) and trying to set realistic expectations.

Last edited: Dec 27, 2025 at 3:41 AM
37 1JessicaM_2024, TomFromTexas, mike.trainer_LA and 34 others
Reply Quote Save Share Report
Dr.AddMedPHL
Senior Member
1,234
6,234
Mar 2024
Philadelphia, PA
Dec 26, 2025 at 11:58 PM#10

To answer sophie_paris's question specifically:

From a clinical standpoint, SOUL trial preliminary data is an area where we have good evidence.

The short answer: baseline labs + quarterly monitoring is the standard of care.

The longer answer involves understanding the mechanism of action at the receptor level, which I am happy to elaborate on if helpful.

34 23JessicaM_2024, TomFromTexas, mike.trainer_LA and 31 others
Reply Quote Save Share Report

Similar Threads

SELECT trial: 20% MACE reduction — mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation — hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists — any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register