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ForumsCardiovascular OutcomesGLP-1 and atrial fibrillation risk — 6 month update Page 3

GLP-1 and atrial fibrillation risk — 6 month update

Dr.LeslieOBGYN Mon, Dec 22, 2025 at 9:46 AM 12 replies 852 viewsPage 3 of 3
sarah_TO
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Sep 2024
Toronto, CA
Dec 22, 2025 at 2:01 PM#11

hannah_MT — wow. I've been looking for this exact info for weeks.

26 9andrew_nyc, Dr.EndoEP, GraceAZ_72 and 23 others
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sophie_paris
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Nov 2024
Paris, FR
Dec 22, 2025 at 2:18 PM#12

Slightly tangential to GLP-1 and atrial but Dr.LeslieOBGYN reminded me — has anyone else noticed changes in their alcohol tolerance?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

31 8CryptoCarl, MariaRD, AussieAnna and 28 others
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MikeKY_noInsulin
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Oct 2024
Louisville, KY
Dec 22, 2025 at 2:35 PM#13

Thanks for sharing this, Dr.LeslieOBGYN. A few questions about your GLP-1 and atrial experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about GLP-1 and atria?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

Last edited: Dec 22, 2025 at 5:35 PM
8 18Dr.SportsMedIN, amy_econ_NJ, bbq_ray_KC and 5 others
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Dr.LeslieOBGYN
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May 2024
Dallas, TX
Dec 22, 2025 at 2:52 PM#14

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on GLP-1 and atrial.

To answer sophie_paris: I get my labs done through Quest every 3 months.

Quick update: my latest labs came back even better. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

50 3NicoleRaleigh, james_edin, FranDenver and 47 others
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TirzTom
Senior Member
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Feb 2024
Florida
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Dec 22, 2025 at 3:09 PM#15

Relevant to GLP-1 and atrial fibrillation — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 199 → 99 mg/dL, hsCRP 6.0 → 1.1 mg/L. All on tirzepatide for 15 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

30 11DeniseRN_TPA, SandraNC_45, Dr.EndoIndy and 27 others
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