Dec 17, 2025 at 11:24 PM#6
Subscribing to this thread. Echocardiographic changes is exactly what I've been researching. 🙏
32 21SkepticalSean, Dr.CardioMD, EndoResFellow and 29 others
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Dec 17, 2025 at 11:41 PM#7
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Echocardiographic changes.
To answer TirzTom: I started tracking everything in a spreadsheet from day 1.
Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Last edited: Dec 18, 2025 at 5:41 AM
12 4wendy_avl, jason_paloalto, Dr.LeslieOBGYN and 9 others
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Dec 17, 2025 at 11:58 PM#8
Adding my data to this Echocardiographic changes discussion:
| Metric | Baseline | Month 4 | Month 8 |
|---|---|---|---|
| Weight | 278 lbs | 233 lbs | 223 lbs |
| A1C | 7.2% | 6.2% | 5.4% |
| hsCRP | 7.0 | 3.0 | 1.2 |
Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.5g/kg/day.
11 15RetaRick_CA, JenPlateau, SallyK_inj and 8 others
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Verify Your PeptidesDec 18, 2025 at 12:15 AM#9
+1 to NeuroNate. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with Echocardiographic changes.
46 2JessicaM_2024, TomFromTexas, mike.trainer_LA and 43 others
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Dec 18, 2025 at 12:32 AM#10
Slightly tangential to Echocardiographic changes but LarryQC_SD reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
40 7NurseLeah_Nash, gary_naperville, sean_dublin and 37 others
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