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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesCoronary artery calcium score changes on GLP-1 — what worked for you? Page 2

Coronary artery calcium score changes on GLP-1 — what worked for you?

kate.chem Sat, Dec 13, 2025 at 4:22 AM 10 replies 783 viewsPage 2 of 2
LibrarianMeg
Senior Member
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Mar 2024
Baltimore, MD
Dec 13, 2025 at 7:12 AM#6
anders_CPH said:
— in my experience this comes down to a few key factors

Gonna push back on this one. Coronary artery calcium score is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

49 2Dr.NateNeph, PharmD_Rodriguez, julia.endo and 46 others
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dan_philly
Member
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2,123
Jul 2024
Philadelphia, PA
Dec 13, 2025 at 7:29 AM#7

Adding my data to this Coronary artery calcium discussion:

MetricBaselineMonth 5Month 6
Weight272 lbs217 lbs197 lbs
A1C6.6%6.0%5.2%
hsCRP6.04.00.6

Protocol: Semaglutide 1.7mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.

14 21AmyNC_wife, SkepticalSean, Dr.CardioMD and 11 others
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cory_ATX
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Austin, TX
Dec 13, 2025 at 7:46 AM#8

ingrid_STO — wow. This community is amazing.

Last edited: Dec 13, 2025 at 9:46 AM
13 23mona_PHX, andrew_nyc, Dr.EndoEP and 10 others
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SurmountFan_IN
Member
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May 2024
Indianapolis, IN
Dec 13, 2025 at 8:03 AM#9

Slightly tangential to Coronary artery calcium but stefan_berlin reminded me — what is the latest on the oral formulations?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Dec 13, 2025 at 9:03 AM
48 14rachel_ABQ, traveltech_sara, AttorneyGrant and 45 others
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mike_mod
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Dec 13, 2025 at 8:20 AM#10

Moderator note: Please keep vendor-specific discussions in the Vendor Reviews section.

I have cleaned up a few off-topic posts. 👍

36 19PurityPaulOR, MaxMetOK, MounjBrad and 33 others
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