PharmacoVig_BOS said:

Compounded sema potency testing is not that straightforward in my experience

This is exactly right. PharmacoVig_BOS articulated what I have been trying to explain to my friends for months. The Compounded sema potency aspect is what made the difference for me.

Reading this thread on Compounded sema potency hits close to home. Dad of 2 checking in — I started at 261 lbs and felt like I would tried everything.

7 months on tirz and I am a different person. Not just the 36 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Compounded sema — take the leap. It was the best health decision I have ever made. ❤️

CarlaRPh_TPA — that is really helpful context on Compounded sema potency. Follow-up question: how long did you wait before increasing your dose?

I am in a similar situation (week 4) and trying to set realistic expectations.

To answer andrew_nyc's question specifically:

From a clinical standpoint, Compounded sema potency is a reasonable concern that deserves a thorough answer.

The short answer: the evidence supports this approach for most patients.

The longer answer involves reviewing the specific clinical trial data relevant to your question, which I am happy to elaborate on if helpful.

Bookmarked 📌 The Compounded sema info in this thread is essential. Coming back to this for sure.