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ForumsClinical Trials & ResearchTRIUMPH program (retatrutide) — Phase 3 trial design and endpoints Page 3

TRIUMPH program (retatrutide) — Phase 3 trial design and endpoints

TrialTracker_MD Fri, Mar 13, 2026 at 4:40 AM 13 replies 202 viewsPage 3 of 3
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Mar 13, 2026 at 8:55 AM#11

Moderator note: Reminder: nothing posted here constitutes medical advice. Consult your healthcare provider.

Tagging this for the weekly digest. 👍

28 3PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 25 others
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InsuranceTom
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Mar 13, 2026 at 9:12 AM#12

Slightly tangential to TRIUMPH program but TrialNerd_Beth reminded me — does anyone have experience combining this with metformin?

I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.

Last edited: Mar 13, 2026 at 2:12 PM
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mia_MS2
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Mar 13, 2026 at 9:29 AM#13
jason_sac26 said:
Follow-up question: how long did you wait before increasing your dose

This is exactly right. jason_sac26 articulated what I have been trying to explain to my doctor for months. The TRIUMPH program aspect is the most important factor.

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LondonLisa
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Mar 13, 2026 at 9:46 AM#14

Saving this for reference. Top-tier content.

Last edited: Mar 13, 2026 at 11:46 AM
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NicoleRaleigh
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Mar 13, 2026 at 10:03 AM#15

Adding my data to this TRIUMPH program discussion:

MetricBaselineMonth 3Month 8
Weight266 lbs216 lbs201 lbs
A1C7.0%5.8%5.4%
hsCRP5.02.00.8

Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.3g/kg/day.

49 14mike_nyc, VendorMark, COA_Karl and 46 others
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