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Evidence-based GLP-1 & peptide discussion since 2023
ForumsTirzepatide (Mounjaro / Zepbound)Zepbound vs Mounjaro — need advice Page 3

Zepbound vs Mounjaro — need advice

steve_okc Fri, Oct 3, 2025 at 3:17 AM 12 replies 1,138 viewsPage 3 of 3
SarahChen_PharmD
VIP Member
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Dec 2023
San Diego, CA
Oct 3, 2025 at 7:32 AM#11

Subscribing to this thread. Zepbound vs Mounjaro is exactly what I've been researching. 🙏

17 17Dr.ObesityLA, NurseKim_ATL, paul_denver and 14 others
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NauseaFreeNow
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345
1,234
Aug 2024
Indiana
Oct 3, 2025 at 7:49 AM#12

Reading this thread on Zepbound vs Mounjaro hits close to home. Dad of 2 checking in — I started at 269 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 44 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Zepbound vs Mounjaro — take the leap. It was the best health decision I have ever made. ❤️

47 7maya_sedona, stefan_berlin, Dr.EM_Chicago and 44 others
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Admin
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Oct 2023
Online
Oct 3, 2025 at 8:06 AM#13

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

15 8RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 12 others
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dan_philly
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Jul 2024
Philadelphia, PA
Oct 3, 2025 at 8:23 AM#14

Relevant to Zepbound vs Mounjaro need — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 201 → 101 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

6 5Dr.CardioMD, EndoResFellow, PharmacoVig_BOS and 3 others
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FranDenver
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Oct 2024
Denver, CO
Oct 3, 2025 at 8:40 AM#15

Congrats SarahChen_PharmD!! You should be so proud of yourself. 🎉 👏

21 11GenomicsKate, Dr.ObesityMed, HealthEcon_DC and 18 others
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