Mar 5, 2026 at 10:52 PM#6
Subscribing to this thread. Mazdutide (LY3305677) is exactly what I've been researching. 🙏
Last edited: Mar 5, 2026 at 11:52 PM
33 6Admin, Dr.Martinez, mike_mod and 30 others
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Mar 5, 2026 at 11:09 PM#7
OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on Mazdutide (LY3305677) .
To answer Dr.ObesityLA: I started tracking everything in a spreadsheet from day 1.
Quick update: I will post a proper update thread soon. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏
Last edited: Mar 6, 2026 at 3:09 AM
35 22PharmHunterJen, TomTeleRx, DoseLogDan and 32 others
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Mar 5, 2026 at 11:26 PM#8
Adding my data to this Mazdutide (LY3305677) discussion:
| Metric | Baseline | Month 4 | Month 8 |
|---|---|---|---|
| Weight | 250 lbs | 230 lbs | 205 lbs |
| A1C | 6.4% | 6.2% | 5.4% |
| hsCRP | 4.0 | 3.0 | 0.8 |
Protocol: Tirzepatide 15mg/wk, resistance training 3x/wk, protein 1.2g/kg/day.
15 7maya_sedona, stefan_berlin, Dr.EM_Chicago and 12 others
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View ResultsMar 5, 2026 at 11:43 PM#9
+1 to TrialNerd_Beth. Especially the point about "Thank you all for the thoughtful replies..." — I have seen the same in my own experience with Mazdutide (LY3305677) .
43 2sean_dublin, hannah_MT, Dr.SportsMedIN and 40 others
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Mar 6, 2026 at 12:00 AM#10
Slightly tangential to Mazdutide (LY3305677) but pam_columbus reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
30 0PharmHunterJen, TomTeleRx, DoseLogDan and 27 others
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