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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesHas anyone dealt with my dad had a heart attack and now i am terrified - will glp-1 help?? Page 3

Has anyone dealt with my dad had a heart attack and now i am terrified - will glp-1 help??

chris_chi24 Wed, Oct 15, 2025 at 1:08 PM 18 replies 1,212 viewsPage 3 of 4
Admin
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Oct 15, 2025 at 5:23 PM#11

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

Last edited: Oct 15, 2025 at 9:23 PM
14 10PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 11 others
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LibrarianMeg
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Oct 15, 2025 at 5:40 PM#12

Clinical perspective on Has anyone dealt with my dad had a heart:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

24 23PharmD_Rodriguez, julia.endo, JessicaM_2024 and 21 others
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PharmacoVig_BOS
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Oct 15, 2025 at 5:57 PM#13
Admin said:
Just a reminder to keep things civil and evidence-based

I respect Admin perspective but I think this oversimplifies things a bit. Re: Has anyone dealt with my dad — the effect size varies considerably by population.

I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

30 1DataDave, Dr.GutHealth, amsterdam_pete and 27 others
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kim_atl_prep
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Oct 15, 2025 at 6:14 PM#14

Reading this thread on Has anyone dealt with my hits close to home. Dad of 2 checking in — I started at 269 lbs and felt like I would tried everything.

15 months on tirz and I am a different person. Not just the 44 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Has anyone dealt — take the leap. It was the best health decision I have ever made. ❤️

25 8SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 22 others
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JenPlateau
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Oct 15, 2025 at 6:31 PM#15

Bookmarked 📌 The Has anyone dealt info in this thread is essential. Coming back to this for sure.

Last edited: Oct 16, 2025 at 12:31 AM
14 23sarah_nash92, FitDadDave, RunnerRach and 11 others
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