Relevant to Loose skin after major weight — here is my latest bloodwork comparison:

Key improvements: A1C 7.2% → 5.3%, triglycerides 203 → 103 mg/dL, hsCRP 6.0 → 0.9 mg/L. All on tirzepatide for 7 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

Want to share my personal experience related to Loose skin after major weight since I think it might help others in a similar situation.

I started my GLP-1 journey in October 2024 at 274 lbs with prediabetes and hypertension. My endocrinologist prescribed semaglutide 0.25mg to start.

Now, 10 months later: I am down 64 lbs, my labs have normalized, and I am off 2 of my 3 medications. The Loose skin after aspect specifically was something that made a big difference in my journey.

This community helped me every step of the way.

CanadaChris — that is really helpful context on Loose skin after major. Follow-up question: did you experience any side effects during this phase?

I am in a similar situation (about to start) and trying to set realistic expectations.

Want to share my personal experience related to Loose skin after major weight since I think it might help others in a similar situation.

I started my GLP-1 journey in March 2025 at 246 lbs with metabolic syndrome. My telehealth provider prescribed semaglutide 0.25mg to start.

Now, 16 months later: I am down 71 lbs, my labs have normalized, and my sleep apnea has improved dramatically. The Loose skin after aspect specifically was something that made a big difference in my journey.

This forum was my go-to resource throughout.

zoe_NC — that is really helpful context on Loose skin after major. Follow-up question: did you change anything about your diet at the same time?

I am in a similar situation (month 2) and trying to set realistic expectations.