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ForumsCompounding & FormulationBeyond-use dating: 28 days vs 60 days — looking for input Page 4

Beyond-use dating: 28 days vs 60 days — looking for input

DoseLogDan Sun, Jan 19, 2025 at 6:42 AM 35 replies 1,751 viewsPage 4 of 7
JessicaM_2024
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Jan 19, 2025 at 12:22 PM#16

Just wanted to say — for anyone reading this Beyond-use dating 28 thread who is feeling discouraged: it gets better. The first 6 weeks are the hardest. Hang in there. 💪

6 1james_edin, FranDenver, Dr.BariatricHTX and 3 others
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Dr.SurgeonPGH
Senior Member
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Pittsburgh, PA
Jan 19, 2025 at 12:39 PM#17

As a pharmacist, I want to add some clinical context to this discussion on Beyond-use dating 28 days vs 60 days .

Building on what JennaRN said — the evidence base here is robust. The key publications to reference are from the SUSTAIN program[1].

Key clinical points:

  1. Efficacy is dose-dependent and typically requires 4-5 weeks to reach steady state
  2. Side effect profile is predictable and usually manageable with standard protocols
  3. Monitoring should include baseline labs and follow-up at 3-month intervals
  4. Patient education significantly improves outcomes and adherence

Standard disclaimer: this is educational, not individualized medical advice.

References:
[1] See thread title for relevant study identification.
7 13TomTeleRx, DoseLogDan, SleepFixSam and 4 others
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PharmacoVig_BOS
Senior Member
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Feb 2024
Boston, MA
Jan 19, 2025 at 12:56 PM#18
JessicaM_2024 said:
The first 6 weeks are the hardest

Gonna push back on this one. Beyond-use dating 28 days vs 60 is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong — the medication works. But cost accessibility is a real barrier. We should be honest about that.

Last edited: Jan 19, 2025 at 3:56 PM
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greg_boulder
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Jul 2024
Boulder, CO
Jan 19, 2025 at 1:13 PM#19

Subscribing to this thread. Beyond-use dating 28 days is exactly what I've been researching. 🙏

Last edited: Jan 19, 2025 at 3:13 PM
23 12patPC_UT, Dr.DermMIA, fiona_VT and 20 others
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mel_PDX
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Dec 2024
Portland, OR
Jan 19, 2025 at 1:30 PM#20

Reading this thread on Beyond-use dating 28 days hits close to home. Night shift nurse — I started at 275 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 50 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Beyond-use dating 28 — take the leap. It was the best health decision I have ever made. ❤️

29 11RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 26 others
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