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ForumsCompounding & FormulationMy vial looks cloudy - throw it out?? — 6 month update

My vial looks cloudy - throw it out?? — 6 month update

A1cHero_PHX Sun, Dec 29, 2024 at 2:35 PM 14 replies 1,750 viewsPage 1 of 3
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A1cHero_PHX
Member
523
2,678
Jul 2024
Phoenix, AZ
Dec 29, 2024 at 4:00 PM#1

My endo and I disagree about my vial looks cloudy - throw and I want a reality check.

They are saying that I do not need to worry about it but everything I have read here suggests otherwise.

I trust this community's collective knowledge but I also do not want to go against medical advice without good reason. What would you do?

23 10zoe_NC, Dr.ObesityLA, NurseKim_ATL and 20 others
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Dr.NateNeph
VIP Member
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16,234
Dec 2023
Houston, TX
Dec 29, 2024 at 4:17 PM#2

A1cHero_PHX's experience with My vial looks cloudy - resonates deeply with mine. I went through almost the identical process — starting dose, titration timeline, side effects, everything.

The main difference: I titrated faster. But the overall trajectory has been remarkably similar. Down 60 lbs in 5 months.

One thing I would add that A1cHero_PHX did not mention: the relationship with food fundamentally changed.

35 11NauseaFreeNow, SteveThurs, B12Beth and 32 others
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KristenIndy
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May 2024
Indianapolis, IN
Dec 29, 2024 at 4:34 PM#3

Thanks for sharing this, A1cHero_PHX. A few questions about your My vial looks cloudy experience:

  1. What dose did you start at?
  2. How long before you noticed side effects improving?
  3. Did your provider have any specific recommendations about My vial looks?

I am in a similar boat and trying to learn from others' experiences before my next appointment.

43 5Dr.GutHealth, amsterdam_pete, LondonLisa and 40 others
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A1cHero_PHX
Member
523
2,678
Jul 2024
Phoenix, AZ
Dec 29, 2024 at 4:51 PM#4

OP here — wow, did not expect this much response! Thank you all for the thoughtful replies on My vial looks cloudy -.

To answer KristenIndy: yes, I am on compounded sema from a 503B pharmacy.

Quick update: things are still going well. Thanks again for the evidence-based discussion — this is exactly why I posted in a science-based community. 🙏

45 1chris_chi24, tampaLisa73, KarenAZ_mom and 42 others
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hank_denver
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Sep 2024
Denver, CO
Dec 29, 2024 at 5:08 PM#5

Relevant to My vial looks cloudy - throw — here is my latest bloodwork comparison:

Key improvements: A1C 7.6% → 5.5%, triglycerides 193 → 93 mg/dL, hsCRP 8.0 → 1.1 mg/L. All on tirzepatide for 9 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

39 9Dr.DermMIA, fiona_VT, denise_HTX and 36 others
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