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Evidence-based GLP-1 & peptide discussion since 2023
ForumsTirzepatide (Mounjaro / Zepbound)Has anyone dealt with tirzepatide and fatty liver? Page 3

Has anyone dealt with tirzepatide and fatty liver?

Dr.PeteFamMed Sat, Aug 23, 2025 at 6:29 PM 39 replies 1,964 viewsPage 3 of 8
Admin
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Aug 23, 2025 at 10:44 PM#11

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

Last edited: Aug 24, 2025 at 2:44 AM
33 16PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 30 others
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VendorMark
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Aug 23, 2025 at 11:01 PM#12

Clinical perspective on Has anyone dealt with tirzepatide and:

I have managed roughly 300 patients on GLP-1 therapy and this topic comes up frequently. What the data shows — and what I see in practice — is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

7 7KristenIndy, MarkLI_maint, Dr.PeteFamMed and 4 others
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julia.endo
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Aug 23, 2025 at 11:18 PM#13
Admin said:
Just a reminder to keep things civil and evidence-based

I respect Admin perspective but I think this oversimplifies things a bit. Re: Has anyone dealt with — the effect size varies considerably by population.

I am not saying Admin wrong entirely — just that the picture is more nuanced than a blanket statement. The STEP data specifically shows dose-dependent variation.

25 3hans_munich, jason_sac26, chris_chi24 and 22 others
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robert_kc
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Aug 23, 2025 at 11:35 PM#14

Reading this thread on Has anyone dealt with hits close to home. Dad of 2 checking in — I started at 297 lbs and felt like I would tried everything.

13 months on tirz and I am a different person. Not just the 72 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about Has anyone dealt — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Aug 24, 2025 at 1:35 AM
7 9TomTeleRx, DoseLogDan, SleepFixSam and 4 others
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kevin_tulsa
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Aug 23, 2025 at 11:52 PM#15

Bookmarked 📌 The Has anyone dealt info in this thread is essential. Coming back to this for sure.

15 19NurseLeah_Nash, gary_naperville, sean_dublin and 12 others
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