JennaRN said:Short answer: talk to your prescriber first
Gonna push back on this one. Efinopegdutide MASH-focused is not that straightforward in my experience. I have been on this for 18 months and the reality is messier than the trials suggest.
Don't get me wrong — the medication works. But adherence is harder than people admit. We should be honest about that.
Adding my data to this Efinopegdutide discussion:
| Metric | Baseline | Month 3 | Month 8 |
|---|---|---|---|
| Weight | 262 lbs | 247 lbs | 207 lbs |
| A1C | 6.6% | 5.8% | 5.4% |
| hsCRP | 6.0 | 2.0 | 1.2 |
Protocol: Semaglutide 2.4mg/wk, resistance training 3x/wk, protein 1.4g/kg/day.
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View ResultsSlightly tangential to Efinopegdutide but SleepDoc_PDX reminded me — has anyone else noticed changes in their alcohol tolerance?
I know it is not exactly on-topic but it seems related enough to ask here rather than starting a new thread. Apologies if this has been covered — I did search first.
Moderator note: This thread has been getting great engagement. Please remember to cite sources when making clinical claims.
No issues to report — carry on. 👍