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Evidence-based GLP-1 & peptide discussion since 2023
ForumsTirzepatide (Mounjaro / Zepbound)GIP receptor: the underappreciated half of tirzepatide's mechanism — need advice Page 3

GIP receptor: the underappreciated half of tirzepatide's mechanism — need advice

Dr.EM_Chicago Sat, Aug 9, 2025 at 7:40 AM 15 replies 1,283 viewsPage 3 of 3
carlos_SATX
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Oct 2024
San Antonio, TX
Aug 9, 2025 at 11:55 AM#11

Subscribing to this thread. GIP receptor the is exactly what I've been researching. 🙏

Last edited: Aug 9, 2025 at 1:55 PM
48 6james_edin, FranDenver, Dr.BariatricHTX and 45 others
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LabKate
Senior Member
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11,234
Jan 2024
Oregon
Aug 9, 2025 at 12:12 PM#12

Reading this thread on GIP receptor the hits close to home. Dad of 2 checking in — I started at 285 lbs and felt like I would tried everything.

11 months on tirz and I am a different person. Not just the 60 lbs lost — my energy, my mood, my relationship with food. All transformed.

If you are on the fence about GIP receptor the — take the leap. It was the best health decision I have ever made. ❤️

Last edited: Aug 9, 2025 at 3:12 PM
2 4laura_annarbor, JenMemphis
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Admin
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Online
Aug 9, 2025 at 12:29 PM#13

Moderator note: Great discussion, everyone. Just a reminder to keep things civil and evidence-based.

Thread quality is excellent — keep it up. 👍

28 10RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 25 others
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HPLC_Greg
Senior Member
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8,901
Feb 2024
Research Triangle, NC
Aug 9, 2025 at 12:46 PM#14

Relevant to GIP receptor the — here is my latest bloodwork comparison:

Key improvements: A1C 8.4% → 5.5%, triglycerides 237 → 107 mg/dL, hsCRP 8.0 → 1.3 mg/L. All on tirzepatide for 17 months.

The inflammatory marker drop is what impresses me most. Consistent with the SELECT trial's cardiovascular findings.

6 14Dr.MetabolicMD, RetaRick_CA, JenPlateau and 3 others
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VanRx_Mike
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May 2024
Vancouver, CA
Aug 9, 2025 at 1:03 PM#15

Congrats carlos_SATX!! You should be so proud of yourself. 🎉 👏

Last edited: Aug 9, 2025 at 4:03 PM
21 9mike_mod, SarahChen_PharmD, sarah.morrison and 18 others
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