πŸͺ CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
Forumsβ€ΊCardiovascular Outcomesβ€ΊHas anyone dealt with anti-thrombotic properties of glp-1 receptor activation?

Has anyone dealt with anti-thrombotic properties of glp-1 receptor activation?

rachel_ABQ Sat, Aug 23, 2025 at 5:17 PM 30 replies 1,490 viewsPage 1 of 6
This thread is more than 6 months old. Information may be outdated. Consider searching for more recent discussions.
rachel_ABQ
Member
178
890
Dec 2024
Albuquerque, NM
Aug 23, 2025 at 6:42 PM#1

How do you all handle has anyone dealt with anti-thrombotic properties?

Looking for practical tips, not theoretical. What does your actual routine look like? Step by step if possible.

I have tried what my doctor suggested but it is not working great.

12 17nick_newbie, DadBodDave, AmyNC_wife and 9 others
Reply Quote Save Share Report
mike_nyc
VIP Member
5,678
21,345
Nov 2023
New York
Online
Aug 23, 2025 at 6:59 PM#2
rachel_ABQ said:
Has anyone dealt with anti-thrombotic properties of glp-1 receptor activation?

Gonna push back on this one. Has anyone dealt with is not that straightforward in my experience. I have been on this for 12 months and the reality is messier than the trials suggest.

Don't get me wrong β€” the medication works. But cost accessibility is a real barrier. We should be honest about that.

7 11stefan_berlin, Dr.EM_Chicago, pete_RVA and 4 others
Reply Quote Save Share Report
VendorMark
Senior Member
3,456
14,567
Jan 2024
Texas
Online
Aug 23, 2025 at 7:16 PM#3
rachel_ABQ said:
Has anyone dealt with anti-thrombotic properties of glp-1 receptor activation?

This is exactly right. rachel_ABQ articulated what I have been trying to explain to my doctor for months. The Has anyone dealt with aspect is the most important factor.

24 18MarkLI_maint, Dr.PeteFamMed, claudia_zurich and 21 others
Reply Quote Save Share Report

Janoshik Analytical β€” Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides
Dr.LeslieOBGYN
Member
567
2,567
May 2024
Dallas, TX
Aug 23, 2025 at 7:33 PM#4

Clinical perspective on Has anyone dealt with anti-thrombotic:

I have managed ~150 patients on GLP-1 therapy and this topic comes up frequently. What the data shows β€” and what I see in practice β€” is that proper titration prevents most adverse events.

For this specific question, I would recommend: reviewing the relevant clinical guidelines.

Last edited: Aug 24, 2025 at 1:33 AM
19 13NicoleRaleigh, james_edin, FranDenver and 16 others
Reply Quote Save Share Report
DebRD_ATL
Senior Member
1,678
7,890
Feb 2024
Atlanta, GA
Aug 23, 2025 at 7:50 PM#5
VendorMark said:
This is exactly right

I respect VendorMark perspective but I think this oversimplifies things a bit. Re: Has anyone dealt with β€” the effect size varies considerably by population.

I am not saying VendorMark wrong entirely β€” just that the picture is more nuanced than a blanket statement. The SURMOUNT data specifically shows baseline BMI-dependent responses.

Last edited: Aug 23, 2025 at 11:50 PM
12 15HealthEcon_DC, PedsEndoPhilly, SleepDoc_PDX and 9 others
Reply Quote Save Share Report
123…6

Similar Threads

SELECT trial: 20% MACE reduction β€” mechanistic deep dive7 replies
Semaglutide cardiovascular benefit independent of weight loss11 replies
STEP-HFpEF: semaglutide in heart failure with preserved EF15 replies
GLP-1 and arterial inflammation β€” hsCRP and IL-6 reduction data18 replies
Lp(a) on GLP-1 agonists β€” any impact on this risk factor?8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register